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Babies Lost to Miscariagge by UN Personnel 2 in Haiti...

Dlobondye Says...

Babies Lost to Miscariagge by UN Personnel 2004-2021 in Haiti.

The team started with a series of 1,527 single-child pregnancies that ended in a loss that were sent to Kliman's consult service at Yale for evaluation.

After excluding cases without adequate material for examination, 1,256 placentas from 922 patients were examined.

Of these, 70% were miscarriages and 30% were stillbirths.

By adding the explicit categories of "placenta with abnormal development" (dysmorphic placentas) and "small placenta" (a placenta less than the 10th percentile for gestational age) to the existing categories of cord accident, abruption, thrombotic, and infection, for example, the authors were able to determine the pathologic diagnoses for 91.6% of the pregnancies, including 88.5% of the miscarriages and 98.7% of the stillbirths.

The most common pathologic feature observed in unexplained miscarriages were dysmorphic placentas (86.2%), a marker associated with genetic abnormalities.

The most common pathologic feature observed in unexplained stillbirths was a small placenta (33.9%).

"This work suggests that the over 7,000 small placentas per year associated with stillbirths could have been detected in utero -- flagging those pregnancies as high risk prior to the loss," said Kliman.

"Likewise, the identification of dysmorphic placentas may be one way to potentially identify genetic abnormalities in the almost 1 million miscarriages that occur in our country every year."

He added, "Having a concrete explanation for a pregnancy loss helps the family understand that their loss was not their fault, allows them to start the healing process, and, when possible, prevent similar losses -- especially stillbirths -- from occurring in the future."

When asked what the most effective way might be to prevent stillbirths, Kliman responded, "Measure the placenta!"

Posted September 23 2023 at 5:38 PM

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